Antigravity Science Plugin - Interactive 3D Biomolecular & Variant Studio

1. Load Structure (`load_structure`) QC: PASS

TP53 Tumor SuppressorAF-P04637

AlphaFold core DNA-binding domain + disordered transactivation N-tail & R248Q hotspot.

Crambin + Linker1CRN-QC

Disulfide-stabilized plant protein with flexible N-terminal linker & active site annotations.

EGFR Kinase + GefitinibCHEMBL203

ATP-binding cleft with L858R oncogenic variant & ChEMBL inhibitor pocket (`IC50 = 33 nM`).

+ Upload Local .PDB / .CIF File into Viewer

2. MCP Representation (`set_representation`)

Color Scheme

3D Style & Overlays

MCP Tool Quick Actions (`science_biomolecular_structure_viewer_mcp`)

Active Sidecar: sidecar://science/biomolecular_structure_viewer/ui.html
Click any 3D C-alpha residue sphere to inspect pLDDT, AlphaGenome AVI & pin an MCP annotation.

Selected Residue: R248 (Chain A)
pLDDT: 94.6 | AVI Impact: 0.96 (Pathogenic)

Very High (≥90) Confident (70–90) Low (50–70) Disordered (<50) Variant Hotspot

Drag to rotate • Scroll to zoom • Click atom to annotate

3. PAE Matrix & Structure QC (`audit_structure.py`)

C-Alpha Residues48

Mean pLDDT81.4

Confident (≥70)79.2%

Disordered (<50)14.6%

Rigid Core SpanRes 8–45

4. Live MCP Tool Call Stream (`mcp_entry.cjs`)

5. Bonus Skill: `predictingthepast` (Aeneas Latin)

Damaged Inscription Input (`?` = 1 char):

imp caesar divi f ???????? cos xi

Click Run Aeneas to restore gap & attribute province/date.